Foxo4
Description
A synthetic D-retro-inverso peptide designed to selectively disrupt the FOXO4-p53 interaction, researched for its targeted role in inducing apoptosis in senescent cells and promoting tissue rejuvenation models.
Available in 10mg vials, every lot is third-party tested for identity and purity, with certificates of analysis available on request. Vials arrive sealed and sterile, lyophilized for stability, and ship from our U.S. facility in 2–6 days.
For in vitro laboratory research use only. See the Technical Data tab below for the full mechanism and feature summary.
Foxo4 from Wolf Research is a high-purity research-grade compound intended strictly for laboratory research use.
Foxo4 (FOXO4-DRI (D-Retro-Inverso FOXO4 p53-interacting peptide)) is supplied as a research-grade peptide for in vitro study. Synthetic research peptides of this class are widely used in laboratory studies of receptor signaling, tissue biology, and peptide pharmacology.
Every lot of Foxo4 is third-party tested for identity and purity, with certificates of analysis available on request. Supplied in sealed, sterile vials and shipped fast from our U.S. facility.
The products offered herein are intended exclusively for research purposes and must be utilized solely within in vitro environments (e.g., test tubes or laboratory settings) for the purposes of testing and experimentation. All information provided on this website is strictly for educational purposes and does not constitute legal or professional advice. It is imperative to acknowledge that the introduction of these products into humans or animals, in any capacity, is strictly prohibited by applicable laws and regulations. Violation of these regulations may result in legal repercussions. These products are intended solely for use by qualified, licensed professionals with the expertise to handle them safely and responsibly. Furthermore, it is important to note that these products are not classified as drugs, food, or cosmetics under any legal definitions. Any misbranding, misuse, or mislabeling of these products within these categories is expressly prohibited and may lead to further legal consequences. By adhering to these guidelines, you ensure compliance with all regulatory frameworks and contribute to the responsible conduct of scientific research.
Technical Data
| A synthetic D-retro-inverso peptide designed to selectively disrupt the FOXO4-p53 interaction, researched for its targeted role in inducing apoptosis in senescent cells and promoting tissue rejuvenation models. | |
|---|---|
| Key Benefits & Highlights | |
| Targeted Senolytic Mechanism | Selectively targets senescent cells by disrupting the FOXO4-p53 complex, releasing p53 to trigger apoptosis specifically in non-dividing, damaged cells. |
| Tissue Regeneration & Rejuvenation | Researched in cellular and animal models for its potential to improve organ function, restore tissue vitality, and counteract age-related biological decline. |
| Preservation of Healthy Cells | Engineered with a D-retro-inverso configuration for high structural stability while sparing healthy, non-senescent cells. |
| High Chemical Purity | Synthesized to exacting standards to maintain precise peptide sequence fidelity and minimize experimental variance. |
| Standardized Research Reagent | Formulated for reliable performance across in vitro senolytic assays, cellular longevity studies, and tissue repair research. |
| Feature Summary | |
| Product Class | Synthetic D-Retro-Inverso Peptide / Targeted Senolytic Agent |
| Primary Application | In vitro senolysis, FOXO4-p53 pathway & anti-aging research |
| Grade | Laboratory / Research Grade Only |